منابع مشابه
Gastroduodenal mucosal alkaline secretion and mucosal protection.
The gastroduodenal mucosa is a dynamic barrier restricting entry of gastric acid and other potentially hostile luminal contents. Mucosal HCO3(-) is a key element in preventing epithelial damage, and knowledge about HCO3(-) transport processes, including the role of the cystic fibrosis transmembrane conductance regulator channel, and their neurohumoral control are in rapid progress.
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This contribution reviews briefly the history of the discovery and characterization of peptic activity; secretory models and current concepts regarding the regulation of pepsinogen secretion; and evidence that pepsin is a necessary co-factor for gastroduodenal mucosal injury. Several animal studies indicate that peptic activity is required for acid- and nonsteroidal anti-inflammatory drug-induc...
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Well-coordinated mechanisms have evolved that provide both innate protection against gastrointestinal mucosal injury and facilitation of rapid mucosal repair following mucosal damage. Generic protection from injury is provided by intrinsic structural features of the epithelium that form a highly competent barrier and a complex formed at the apical surface by trefoil peptides that comprise the i...
متن کاملEffect of cysteamine on gastroduodenal mucosal histamine in rat.
Cysteamine administration to rats is followed by a high incidence of peptic ulceration. The aim of the present study was to investigate the effect of cysteamine on gastric and duodenal mucosal histamine and gastric mucosal histamine formation capacity. After a four hour fast, cysteamine in doses of 50, 100, 200, 300, 400, and 500 mg/kg bodyweight was injected subcutaneously to male Wistar rats;...
متن کاملInvestigating the Relationship between Defense Mechanisms and Coronavirus Anxiety
The prevalence of Covid- 19 has had various economic, social, and psychological consequences. The aim of this Research was to study the relationship between Corona Disease Anxiety and Defense Mechanisms in the southern region of the country. For this purpose, a sample including adult male and female evaluated online by Corona Disease Anxiety Scale (Alipour, 1398) and the ِdefense mechanisms (And...
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ژورنال
عنوان ژورنال: Current Opinion in Gastroenterology
سال: 2015
ISSN: 0267-1379
DOI: 10.1097/mog.0000000000000211